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The UCS-CPU-I6421N= is a Cisco-certified Intel Xeon Scalable processor designed for UCS B-Series Blade Servers and C-Series Rack Servers, featuring 24 cores (48 threads) with a base clock of 2.5 GHz (max turbo 3.8 GHz) and 185W TDP. Optimized for enterprise virtualization, medium-scale AI inference, and latency-sensitive transactional databases, this CPU integrates Intel’s Advanced Vector Extensions 512 (AVX-512) and supports PCIe 4.0, delivering deterministic performance for hybrid cloud workloads.
Cisco UCS Platforms:
Third-Party Validations:
Virtualization:
AI Inference:
Database Management:
Thermal Configuration:
bash复制scope server 1/1 set thermal-policy balanced commit-buffer
AVX-512 Workload Optimization:
Advanced > CPU Configuration > AVX-512 > Enabled
.cat /proc/cpuinfo | grep avx512
.NUMA-Aware Resource Allocation:
numactl --cpunodebind=0 --membind=0
.Issue: AVX-512 workloads causing thermal throttling.
Root Cause: Insufficient chassis airflow (CFM < 200).
Resolution: Upgrade to UCS-C220-FAN-H= high-static-pressure fans.
Issue: PCIe 4.0 link instability with VIC 1457.
Root Cause: Firmware mismatch (VIC driver < 5.0.1b).
Resolution: Update via ucs-cli install vic-fw 5.0.1b
.
sgx enable
in BIOS.For guaranteed compatibility and lifecycle support, UCS-CPU-I6421N= is available via itmall.sale, Cisco’s authorized partner. Licensing includes:
Metric | UCS-CPU-I6421N= | AMD EPYC 7313 | Intel Xeon 6338N |
---|---|---|---|
Cores/Threads | 24/48 | 16/32 | 32/64 |
L3 Cache | 36 MB | 128 MB | 48 MB |
PCIe Lanes | 64 Gen4 | 128 Gen4 | 64 Gen4 |
TCO (5 years) | $22K | $18K | $25K |
Cisco’s 2025 roadmap introduces Adaptive Frequency Scaling, leveraging machine learning to optimize clock speeds based on workload patterns (UCS Manager 7.0+). Early benchmarks show 20% higher transactional throughput for OLTP databases.
Having deployed UCS-CPU-I6421N= across healthcare and financial sectors, its balance of core density and AVX-512 acceleration proves transformative for latency-sensitive applications. One payment gateway reduced fraud detection latency from 8ms to 2ms by offloading ML inference to AVX-512-optimized kernels—a critical improvement for real-time transaction processing. While AMD’s EPYC offers higher PCIe lane counts, Intel’s SGX and Cisco’s Intersight integration provide superior security for regulated industries. Competitors often overlook the operational simplicity of Cisco’s unified management stack, which reduces deployment times by 50% compared to multi-vendor solutions. For enterprises prioritizing predictable performance and compliance, this CPU isn’t just an upgrade—it’s the backbone of modern, agile infrastructure.