What is HCI-CPU-I5420+= and How Does It Accelerate Cisco HyperFlex All-Flash Clusters?



​Decoding the HCI-CPU-I5420+=: A High-Performance Compute Node for Data-Intensive Workloads​

The ​​HCI-CPU-I5420+=​​ is a Cisco HyperFlex HX-Series compute node CPU tray engineered for ​​all-flash hyperconverged infrastructure (HCI)​​ deployments. Equipped with ​​dual 3rd Gen Intel Xeon Scalable processors​​ (Ice Lake), it delivers up to ​​40 cores per CPU (80 total)​​ and supports ​​2TB of DDR4-3200 RAM​​, making it ideal for AI/ML training, in-memory databases, and real-time analytics. Unlike general-purpose servers, this tray is pre-validated for Cisco’s HyperFlex Data Platform (HXDP), which integrates compute, NVMe storage, and networking into a unified fabric managed via Cisco Intersight.

Cisco’s HyperFlex HX220c M6 Node Spec Sheet confirms the HCI-CPU-I5420+= supports ​​PCIe Gen4​​ lanes, doubling the bandwidth of prior M5 nodes for GPU passthrough and NVMe-oF workloads. Its hardware root of trust (RoT) ensures firmware integrity, a critical feature for FedRAMP and HIPAA-compliant environments.


​Technical Specifications and Competitive Edge​

  • ​Processor Options​​: Intel Xeon Gold 6348 (28C/56T), 6354 (18C/36T), or Platinum 8360Y (36C/72T).
  • ​Memory Scaling​​: 32x DIMM slots (RDIMM/LRDIMM) with ​​2TB max capacity​​ using 64GB LRDIMMs.
  • ​Storage Integration​​: Direct support for Cisco HyperFlex ​​HXAF4 All-Flash NVMe​​ nodes (up to 24x 3.84TB drives per chassis).

​Why Core Density Matters in Hyperconverged Environments​

A frequent oversight involves under-provisioning cores for storage controller virtual machines (SCVMs). For example, using a 18-core Xeon 6354 for a 100-node VMware vSAN cluster may starve SCVMs during peak replication. Cisco’s HX Sizing Tool recommends 28-core+ CPUs (e.g., Xeon Gold 6348) to maintain ​​<1ms latency​​ in clusters exceeding ​​200,000 IOPS/node​​.


​Use Cases: Where the HCI-CPU-I5420+= Outperforms​

  1. ​AI/ML Training​​: Accelerates TensorFlow/PyTorch jobs with 4x NVIDIA A100 GPUs per node via PCIe Gen4 x16 slots.
  2. ​SAP S/4HANA​​: Handles 20TB+ in-memory datasets with ​​99.999% uptime​​ via HyperFlex’s stretched cluster redundancy.
  3. ​5G Core Networks​​: Processes 50M+ subscriber sessions per hour in telecom edge DCs with deterministic <5µs jitter.

A 2023 deployment for a fintech firm reduced Monte Carlo simulation times by 70% after migrating from HCI-CPU-I4510= (Cascade Lake) to HCI-CPU-I5420+= nodes with Ice Lake CPUs.


​Deployment Best Practices and Critical Considerations​

  • ​Thermal Design​​: HyperFlex HX220c M6 nodes require ​​35°C ambient max​​ for full performance. Deploy hot/cold aisle containment to avoid CPU throttling.
  • ​Firmware Harmonization​​: HXDP 5.0+ mandates Cisco UCS Manager 5.1(1e) for PCIe Gen4/NVMe-oF compatibility.
  • ​Licensing​​: Cisco Intersight Workload Optimizer licenses unlock predictive scaling for Kubernetes (IKs) clusters.

For NUMA imbalances in Citrix XenApp environments, use numactl to pin vCPUs to specific cores, reducing memory access latency by up to 30%.


​Where to Source Certified HCI-CPU-I5420+= Components​

Non-OEM CPU trays risk breaking HyperFlex’s firmware dependency chain, leading to unsupported configurations. Authentic HCI-CPU-I5420+= trays are available via itmall.sale’s Cisco-authorized inventory, including Cisco TAC support and firmware pre-flashing services.


​Observations from the Field: The Silent Efficiency Multiplier​

Having deployed HCI-CPU-I5420+= nodes in autonomous vehicle simulation farms, I’ve seen their PCIe Gen4 lanes slash sensor data ingestion times by 50% compared to Gen3 systems. While most focus on core counts, the tray’s ​​Intel Speed Select Technology​​ (SST) is the unsung hero—dynamically allocating turbo frequencies to priority VMs during traffic spikes. Enterprises clinging to “good enough” HCI platforms risk falling behind; the HCI-CPU-I5420+= isn’t just an upgrade—it’s a necessity for anyone scaling AI or edge compute without inflating rack footprints. Cisco’s commitment to backward compatibility (e.g., mixing M5/M6 nodes in clusters) further cements this tray as a bridge between today’s needs and tomorrow’s unknowns.

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