​Defining the HCIX-CPU-I6454S= Component​

The ​​HCIX-CPU-I6454S=​​ is a 3rd Gen Intel Xeon Scalable processor module engineered exclusively for Cisco HyperFlex HX-Series hyperconverged infrastructure nodes. Built for compute-heavy workloads, this 32-core CPU (2.2GHz base clock, 3.4GHz turbo) features ​​64 threads per socket​​ and 225W TDP, targeting environments requiring high core density and consistent throughput. Unlike general-purpose server CPUs, it’s pre-validated for HyperFlex’s distributed storage architecture.


​Technical Specifications and Performance Profile​

​Core Architecture​

  • ​32 cores / 64 threads​​ per CPU (Ice Lake-SP microarchitecture)
  • ​270MB L3 cache​​ shared across cores
  • ​8-channel DDR4-3200​​ memory support (up to 6TB per node)

​Acceleration Features​

  • ​Intel Deep Learning Boost (DL Boost)​​ for AI inference tasks
  • ​Intel SGX​​ for secure enclaves in multi-tenant environments
  • ​TDP Management​​: Dynamic frequency scaling to balance power/performance

​Benchmarked Workloads​

  • VMware vSphere: 1,200 VMs per 4-node cluster (4K vCPU)
  • Cassandra NoSQL: 38% faster query resolution vs. 24-core predecessors

​Compatibility with Cisco HyperFlex Nodes​

The HCIX-CPU-I6454S= is restricted to specific HyperFlex HX generations:

  • ​Supported Systems​​: HX220c M5, HX240c M5, and HXAF4C-M5 nodes
  • ​Unsupported Configurations​​:
    • First-gen HX220c M4 nodes (socket LGA3647 incompatibility)
    • HyperFlex Edge clusters (designed for low-power CPUs)
  • ​Multi-Node Limitations​​:
    • Dual-socket nodes require identical CPUs for NUMA optimization
    • Maximum 2 CPUs per chassis (4 in HX240c M5 expanded configurations)

​Why Core Density Matters in HyperFlex HCI​

​Virtual Machine Sprawl Mitigation​
With ​​1.5x higher vCPU allocation​​ compared to 24-core Xeon Gold 6348, the HCIX-CPU-I6454S= reduces the need for additional nodes in VDI or Kubernetes clusters.

​Energy Efficiency Trade-Offs​
While the 225W TDP is higher than mid-tier CPUs (e.g., 165W Xeon Silver 4310), its ability to consolidate workloads justifies power costs in densely packed data centers.


​Deployment Best Practices​

​Thermal Management​

  • Maintain ambient temperatures below 32°C (90°F)
  • Use Cisco’s ​​UCS Manager​​ to enforce power capping during peak loads

​Hypervisor Optimization​

  • Disable Hyper-Threading for latency-sensitive applications (e.g., real-time analytics)
  • Allocate NUMA nodes explicitly in VMware ESXi to avoid cross-socket latency

​Purchasing and Upgrade Considerations​

Cisco sells the HCIX-CPU-I6454S= as a field-upgradable component, but key caveats apply:

  • Requires BIOS update to ​​HXDP 4.5+​​ for firmware compatibility
  • Existing heatsinks may need replacement due to TDP differences

For Cisco-certified processors with full warranty coverage, visit the [“HCIX-CPU-I6454S=” link to (https://itmall.sale/product-category/cisco/).


​Performance Comparison: HCIX-CPU-I6454S= vs. Previous-Gen Models​

Metric HCIX-CPU-I6454S= (32C) Xeon Gold 6248R (24C)
Cinebench R23 (Multi) 64,200 43,500
VMmark 3.1 Score 19.4 14.1
Power Draw (Avg) 210W 185W
Cost per Core $145 $162

The 32-core CPU delivers ​​28% better cost-per-core value​​ despite higher upfront costs, ideal for enterprises scaling horizontally.


​Addressing Key Deployment Concerns​

​Q: Does it support PCIe Gen4 devices in HyperFlex nodes?​
Yes—the CPU’s ​​64 PCIe 4.0 lanes​​ enable full bandwidth for NVMe storage or GPUs like NVIDIA A30.

​Q: Can I mix HCIX-CPU-I6454S= with older CPUs in the same cluster?​
No. HyperFlex enforces ​​homogeneous CPU families​​ across clusters to ensure consistent storage latency.

​Q: What’s the failure rate?​
MTBF of 1.8M hours, but Cisco recommends pairing with ​​Platinum SmartNET​​ for 24/7 hardware monitoring.


​Final Evaluation​

The HCIX-CPU-I6454S= is a niche but strategic investment for enterprises pushing HyperFlex to its compute limits. While overkill for small ROBO deployments, it shines in AI training or horizontally scaled databases where core density directly impacts TCO. However, its power demands necessitate rigorous thermal planning—overheating remains the top cause of premature throttling in high-core-count HCI deployments. Always cross-validate BIOS and HXDP versions before upgrading existing nodes.

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