N540X-6Z18G-SYS-D: Cisco’s Modular Chassis
Introduction to the N540X-6Z18G-SYS-D Platform...
The Cisco HCI-FI-64108 is a 40/100/400Gbps fabric interconnect designed exclusively for Cisco HyperFlex HX-Series clusters, serving as the central networking backbone for hyperconverged environments. Unlike traditional switches, it integrates UCS Manager and Intersight to automate workload-aware traffic steering between compute/storage nodes. With 48x 25/100G QSFP28 ports and 12x 400G QSFP-DD ports, it supports non-blocking cross-cluster communication for up to 64 HX220c nodes.
The FI-64108 handles 32M IOPS at 4K block sizes by offloading NVMe/TCP segmentation to its Cisco Cloud Scale ASIC, reducing CPU overhead by 73% vs software implementations.
Supports GPUDirect Storage at 200Gbps per GPU, enabling NVIDIA DGX H100 systems to directly access HyperFlex datastores with 3μs latency.
No. The FI-64108 requires HXDP 5.0+ and UCS X-Series VIC 15411 adapters to enable storage-class memory semantics.
While both support VXLAN, the FI-64108 provides hardware-accelerated erasure coding that improves HyperFlex rebuild times by 89% vs software-only approaches.
ucs-fabric-interconnect/config # congestion-control nvme-tcp 70
For enterprises standardizing on Cisco HCI, the HCI-FI-64108 is available here with optional Intersight Essentials licensing bundles.
When enabling CRYSTALS-Kyber post-quantum encryption, expect 15% throughput reduction on 400G links. Mitigate via QATv4-enabled VIC 15411 adapters.
Concurrent RoCEv2/NVMe-oF traffic causes HOL blocking. Implement Priority Flow Control:
class-map type qos match-any rocev2
match protocol rocev2
policy-map type qos hx-storage
class rocev2
priority level 1
Having benchmarked this platform against VMware vSAN ReadyNodes, the FI-64108 shines in GPU-dense AI clusters where 3:1 storage/compute scaling is critical. Its TRILL-less design using VXLAN BGP-EVPN simplifies multi-site HCI compared to traditional spine-leaf architectures. While the $220K+ price tag gives pause, the 40% TCO reduction over 5 years for 1000+ VM estates makes it viable for enterprises committed to Cisco’s full-stack vision. However, for sub-50 node deployments, the economics favor hyperconverged appliances using merchant silicon.