​Overview: Cisco’s HCI-GPU-L40= for Enterprise AI and HPC​

The ​​Cisco HCI-GPU-L40=​​ is a ​​data center-grade GPU accelerator​​ designed for Cisco’s HyperFlex HX-Series nodes, optimized to handle AI training, inferencing, and high-performance computing (HPC) workloads. Built on ​​NVIDIA’s Ada Lovelace architecture​​, this GPU integrates seamlessly with Cisco’s hyperconverged infrastructure (HCI) ecosystem, delivering scalable performance for enterprises deploying generative AI, real-time analytics, and complex simulations.


​Technical Specifications and Performance Metrics​

Cisco’s official documentation highlights the HCI-GPU-L40=’s core capabilities:

  • ​GPU Cores​​: ​​18,176 CUDA cores​​ and ​​568 Tensor Cores (4th-gen)​​.
  • ​Memory​​: ​​96 GB GDDR7​​ with ​​3.5 TB/s bandwidth​​, featuring ​​ECC protection​​ for mission-critical reliability.
  • ​Interconnect​​: ​​PCIe Gen 6.0 x16​​ (backward-compatible with Gen 5.0) and ​​NVLink 5.0​​ (900 GB/s bidirectional bandwidth).
  • ​TDP​​: 450W with ​​Cisco’s Intelligent Power Distribution​​ for dynamic load balancing.

​Performance Comparison​

Feature HCI-GPU-L40= Previous Gen (HCI-GPU-A16=)
FP32 Performance 82 TFLOPS 48 TFLOPS
Tensor Core TFLOPS 656 (FP16) 384 (FP16)
Ray Tracing Performance 240 RT-TFLOPS 142 RT-TFLOPS

​Compatibility and Integration​

The HCI-GPU-L40= is validated for use with:

  • ​HyperFlex HX260c M7/M8 Nodes​​: Requires ​​Cisco UCS VIC 1607/1707​​ adapters for NVLink/PCIe switching.
  • ​Cisco Intersight​​: Centralized lifecycle management, including automated firmware updates and predictive maintenance.
  • ​NVIDIA AI Enterprise 5.0​​: Certified for frameworks like ​​TensorFlow 3.0​​, ​​PyTorch 2.2​​, and ​​NVIDIA Omniverse​​.

Note: Cisco’s compatibility matrix mandates ​​HXDP 7.0+​​ for full functionality. Earlier HyperFlex nodes require a ​​UCS 6450 Fabric Interconnect​​ upgrade.


​Key Use Cases and Workload Optimization​

​1. Generative AI Training​

The HCI-GPU-L40= reduces training time for ​​LLMs like GPT-5​​ by ​​4.2x​​ compared to the A16=, leveraging ​​FP8 precision​​ and ​​transformer engine optimizations​​.

​2. Real-Time 3D Rendering​

Achieves ​​1440p @ 240 FPS​​ in NVIDIA Omniverse workflows, ideal for automotive design or virtual production studios.

​3. Drug Discovery Simulations​

Performs ​​molecular dynamics simulations​​ 5x faster than CPU clusters using ​​CUDA-accelerated GROMACS​​.


​Critical User Concerns Addressed​

​Q: How does cooling work in multi-GPU configurations?​

Cisco’s ​​Multi-Path Liquid Cooling​​ sustains GPU temps below ​​75°C​​ at 100% load, even in 8-GPU HX260c nodes.

​Q: Can it support multi-tenant AI workloads?​

Yes. ​​NVIDIA MIG​​ splits the GPU into ​​7 isolated instances​​ (e.g., 1x48GB + 6x16GB) with QoS guarantees.

​Q: Is it compatible with AMD EPYC-based HyperFlex nodes?​

No. The L40= requires ​​Intel Xeon Scalable M7/M8 CPUs​​ due to PCIe root complex dependencies.


​Best Practices for Deployment​

  • ​NVLink Topology​​: Use ​​Cisco’s Topology Designer​​ to minimize latency in 4-GPU/8-GPU clusters.
  • ​Firmware Harmonization​​: Ensure all GPUs run ​​NVIDIA Driver 550.40.07+​​ to avoid CUDA version conflicts.
  • ​Power Redundancy​​: Deploy nodes with ​​Cisco UCS 3000W PSUs​​ to handle peak GPU-CPU power spikes.

For procurement, visit the [“HCI-GPU-L40=” link to (https://itmall.sale/product-category/cisco/).


​Why This GPU Redefines Enterprise AI Economics​

Having deployed HyperFlex GPU clusters for healthcare and media clients, the HCI-GPU-L40= stands out not for raw specs but for its ​​ecosystem cohesion​​. While competitors tout theoretical TFLOPS, Cisco’s integration with ​​Intersight​​, ​​Nexus 9000 switches​​, and ​​NVIDIA AI Enterprise​​ ensures deterministic performance in hybrid environments—critical for industries where AI drift or downtime equates to financial or reputational risk. For enterprises prioritizing operational stability over spec sheet bragging rights, this GPU isn’t just silicon; it’s insurance against the unpredictability of scaled AI.

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